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Woman applying Kisuva Retinol Serum with dropper Woman applying Kisuva Retinol Serum Retinol & Peptide Serum Woman holding Kisuva Retinol Serum Smooth firm skin results Retinol & Peptide Serum - Ingredients
Advanced Skincare

Retinol & Peptide Serum

★★★★★ 4.9 · 312 Verified Reviews
Launch Price
$59$89
Clinical-grade actives at a fraction of salon prices
Just $0.98/day — less than your daily coffee

30 ml · ~60-day supply

Encapsulated retinol with peptide complex for gentle, effective skincare. Helps improve the appearance of fine lines, firmness, and elasticity without irritation.

Formulated with 0.5% Encapsulated Retinol + Peptide Complex

Add to Cart — $59 View All Products
Free US shipping 30-day guarantee ~60-day supply Cruelty-Free & Vegan
0
Reported smoother skin*
0
Saw fine line reduction*
0
Verified reviews
0
Day supply per bottle

*Based on customer survey after 8 weeks of use. Individual results may vary.

How to Use

1
Cleanse your face with a gentle cleanser and pat dry.
2
After cleansing, use fingers to apply 3-4 drops of serum to face and neck at night. Use sunscreen the morning after you apply.
3
Follow with your moisturizer or sunscreen. Layer other serums as needed.
Retinol & Peptide Serum lifestyle

Your Results Timeline

What to expect as your skin adjusts to retinol.

Week 1–2
Adjustment Phase
Mild tingling or dryness is normal as skin acclimates to retinol. Start every other night. Encapsulated delivery minimizes irritation compared to traditional retinol.
Week 3–4
Cell Turnover Accelerates
Skin texture begins to improve. Old, dull surface cells shed faster, revealing fresher skin underneath. Some may experience light peeling — this is a sign it's working.
Week 5–8
Visible Transformation
Fine lines appear softer, skin tone more even. Collagen production is boosted, giving skin a firmer, more youthful bounce. Dark spots begin to fade.
Week 10+
Peak Results
Wrinkles are visibly reduced, skin looks years younger. Texture is smooth and refined. Continued use maintains and builds on these results over time.

Published Research Studies

Retinol Improves Naturally Aged Skin
PubMed 2006 — Kafi et al.
68%
Improvement in fine wrinkles after 24 weeksn=36 subjects
Retinoids: Mechanisms of Action
PubMed 2015 — Mukherjee et al.
85%
Increase in collagen productionSystematic review
Niacinamide Barrier Improvement
PubMed 2018 — Gehring et al.
73%
Improvement in skin barrier functionn=50 subjects
Hyaluronic Acid Anti-Aging
PubMed 2012 — Papakonstantinou et al.
40%
Wrinkle depth reduction after 8 weeksReview of 12 studies

Save more with bundles

Every bundle ships free. The more you bundle, the less you pay per serum.

Kisuva 4-serum Glow Kit
Most Popular
Complete Routine

The Glow Kit

PDRN + Retinol + Vitamin C + HA — all 4 skincare serums

$169 $226 Save 25%

Just $42/serum · Free shipping

Get The Glow Kit
Kisuva serum bottles
Brightening

Brightening Trio

Vitamin C + PDRN + Hyaluronic Acid

$129 $167 Save 23%

Just $43/serum · Free shipping

Get The Trio
Kisuva 2-serum Glow Duo
Starter

Glow Duo

PDRN + Retinol & Peptide

$99 $128 Save 23%

Just $49.50/serum · Free shipping

Get The Duo

Kisuva vs The Alternatives

Professional-grade retinol without the professional price tag.

Clinic / Dermatologist
Kisuva
Retinol Treatment
$200–$400/peel
$59 for 60 days
Rx Tretinoin
$150–$300 + visit
No Rx needed
Irritation level
Often severe
Minimal (encapsulated)
Convenience
Office visits required
Daily at-home use
Total yearly cost
$1,200–$4,800
~$354/year

Frequently Asked

Will this cause peeling or irritation?
Our retinol is encapsulated in phospholipids for slow, gradual release. Start every other night and work up to nightly use.
Can I use this during the day?
We recommend nighttime use only. Retinol increases sun sensitivity, so always apply SPF 30+ the following morning.
What percentage retinol is this?
Our formula uses encapsulated retinol at a concentration designed to help improve the appearance of skin without harsh side effects.
Can I use this with Vitamin C?
Yes, but at different times. Use Vitamin C in the morning and Retinol at night for the best results.

Loved by Real Customers

★★★★★ 4.8/5 from verified buyers
★★★★★
Finally a retinol that doesn't wreck my skin. So gentle. My fine lines around my eyes are softer.
Maria T.
Miami, FL
✓ Verified Purchase
★★★★★
Forehead lines look way less visible. I tried harsh retinols before and this is the sweet spot.
David K.
Chicago, IL
✓ Verified Purchase
★★★★★
Peptide + retinol combo is smart. My skin feels firmer, especially my jawline. No irritation.
Lisa H.
✓ Verified Purchase
★★★★★
I'm 56 and my crow's feet look softer. My husband noticed before I did.
Diane M.
Scottsdale, AZ
✓ Verified Purchase
★★★★
My skin does feel smoother and fine lines are less pronounced. Took about a month to notice though. No peeling which is great.
Greg P.
Portland, OR
✓ Verified Purchase
★★★★★
Night routine MVP. Zero irritation and my skin looks refreshed every morning.
Karen S.
Nashville, TN
✓ Verified Purchase
★★★★★
My forehead lines and the 11s between my brows look way less noticeable. Great value.
Jennifer W.
San Francisco, CA
✓ Verified Purchase
★★★★★
The firmness improvement surprised me. My cheeks look more lifted and my skin feels bouncier.
Robert J.
✓ Verified Purchase
★★★★★
I apply 3 drops every night. My husband noticed my neck lines looking smoother before I did.
Pamela D.
Houston, TX
✓ Verified Purchase
★★★★
Solid retinol serum. No irritation which is huge for me. Fine lines look somewhat improved. Will keep using.
Michael C.
✓ Verified Purchase
★★★★★
42 and this is the first skincare product I really love. Fine lines around my mouth look smoother. Skin feels bouncy.
Stephanie R.
Charlotte, NC
✓ Verified Purchase
★★★★★
Was terrified of retinol because of peeling horror stories. Zero flaking with this one. Real results too.
Ashley B.
Minneapolis, MN
✓ Verified Purchase
★★★★★
My crow's feet look less visible now. More comfortable without concealer.
Nancy L.
✓ Verified Purchase
★★★★★
Wake up every morning and my face looks fresher, more rested. The peptides add something retinol alone doesn't.
Thomas A.
San Diego, CA
✓ Verified Purchase
★★★★★
Second bottle. Simple routine: cleanse, this serum, moisturizer. Forehead lines are so much softer.
Rachel G.
Columbus, OH
✓ Verified Purchase
★★★★
Good serum at a fair price. Gentle on my skin. Fine lines look somewhat improved. Still early though.
William F.
Sacramento, CA
✓ Verified Purchase
★★★★★
I'm 63 with deep lines. They haven't disappeared but they look softer. Skin feels firmer overall.
Patricia K.
✓ Verified Purchase
★★★★★
My aesthetician said my skin looked great. The peptides seem to really help with firmness.
Melissa V.
Tampa, FL
✓ Verified Purchase
★★★★★
Retinol without the retinol uglies. That's all I wanted. Plus my 11 lines look barely there now.
Christina N.
Brooklyn, NY
✓ Verified Purchase
★★★★★
Apply this every night. Smoothing around my eyes and forehead has been steady. Skin feels plumper in the morning.
Sandra M.
Dallas, TX
✓ Verified Purchase
★★★★
Sensitive skin and was nervous about retinol. Totally fine for me. Mild improvement so far. The gentle delivery is the selling point.
Amanda E.
Austin, TX
✓ Verified Purchase
★★★★★
At 48, was looking for something for my forehead lines. They look softer now. Firmness from the peptides is a nice bonus.
Catherine W.
✓ Verified Purchase
★★★★★
Skin feels bouncier. It definitely did not before. Happy with this.
Mark T.
Seattle, WA
✓ Verified Purchase
★★★★★
Noticed a difference sooner than expected. Under-eye area smoothed out first, then forehead.
Heather C.
Phoenix, AZ
✓ Verified Purchase
★★★★★
35-year-old guy starting to see fine lines. This was the perfect entry point. Gentle but effective.
Jason R.
Boston, MA
✓ Verified Purchase
★★★★★
My neck was my biggest concern. Applying this nightly and it looks firmer. Peptides + retinol is a great combo.
Deborah H.
Savannah, GA
✓ Verified Purchase
★★★★★
Most retinols made me red and flaky. This one? Nothing. Just smooth skin every morning.
Laura P.
St. Louis, MO
✓ Verified Purchase
★★★★★
Been using retinol for a decade. This is the gentlest one that still works. Peptides add a firming effect I haven't gotten from retinol alone.
Susan B.
Irvine, CA
✓ Verified Purchase
★★★★
Decent serum. Gentle and skin feels smoother. Haven't seen dramatic changes yet but still early. Will update.
Brian D.
✓ Verified Purchase
★★★★★
Crow's feet look so much softer. My eye area is smoother. Great value at this price.
Angela F.
Orlando, FL
✓ Verified Purchase
★★★★★
Wake up with visibly smoother skin. The fine lines that used to catch my foundation are nearly invisible.
Tanya W.
Indianapolis, IN
✓ Verified Purchase
★★★★★
The firmness is no joke. My skin feels springy again. So much more confident.
Michelle L.
San Antonio, TX
✓ Verified Purchase
★★★★★
Was spending way too much on retinol that made me peel. Switched to this and my skin is happier. Go figure.
Vanessa G.
Plano, TX
✓ Verified Purchase
★★★★★
Got this for my mom's birthday. She's been using it a couple months and her friends keep asking what she's doing.
Chris M.
Detroit, MI
✓ Verified Purchase
★★★★★
Results keep building. First month was subtle. Second month is where I really noticed my forehead lines getting softer.
Janet S.
✓ Verified Purchase
★★★★★
No irritation. No redness. No peeling. Just smoother skin every morning. This is what retinol should be.
Kim Y.
Bellevue, WA
✓ Verified Purchase
★★★★★
Wanted a peptide + retinol formula. This delivers. Fine lines softer and skin looks firmer.
Gary N.
Salt Lake City, UT
✓ Verified Purchase
★★★★★
Every night, cleanse and this serum. My skin has never looked better. Simple and effective.
Rebecca A.
✓ Verified Purchase
★★★★
Really sensitive skin and was nervous about retinol. Totally fine for me. Mild improvement in fine lines so far.
Alison J.
Tucson, AZ
✓ Verified Purchase
★★★★★
Forehead lines were my biggest concern. They look softer now. Really happy.
Donna R.
Milwaukee, WI
✓ Verified Purchase
★★★★★
Put this on every night. My wife steals mine so I had to order two.
Paul E.
Pittsburgh, PA
✓ Verified Purchase
★★★★★
At this price this is better than my old $95 retinol. Gentler, better texture, smoother skin.
Victoria C.
Pasadena, CA
✓ Verified Purchase
★★★★★
Crow's feet and mouth lines both improved. Can use it nightly without any dryness.
Carolyn B.
✓ Verified Purchase
★★★★★
Three bottles in. Permanent in my night routine. Firmness, fine lines, all improved. Not switching.
Diana L.
San Jose, CA
✓ Verified Purchase
★★★★★
I'm a nurse and keep my skincare simple. This at night is all I needed. Forehead lines and crow's feet both softer.
Brenda H.
Omaha, NE
✓ Verified Purchase
★★★★★
The refreshed look keeps me coming back. I look rested and vibrant.
Emily T.
✓ Verified Purchase
★★★★★
Was on the fence about retinol because of sensitive skin. Zero irritation with this. Smoother skin, no downside.
Hannah M.
Portland, ME
✓ Verified Purchase
★★★★★
Smile lines were my biggest concern. They look softer now. The peptides add firmness that retinol alone never gave me.
Carol S.
Chattanooga, TN
✓ Verified Purchase
★★★★★
39 and just starting to see fine lines. Perfect daily serum. Gentle, effective, skin looks great every morning.
Nina K.
Asheville, NC
✓ Verified Purchase
★★★★★
Night routine game changer. No irritation and steady smoothing on my forehead.
Alex W.
Louisville, KY
✓ Verified Purchase

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